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A2 · Basics

What Is A2 Milk? Meaning, A1 vs A2 & Which Animals Give It

A2 milk is milk whose beta-casein protein is only the A2 type. Ordinary milk from Holstein, Jersey and many crossbred cows contains a mix of A1 and A2. The two differ by one amino acid; digesting A1 can release a peptide called BCM-7. Buffalo milk and milk from most Indian desi cows is A2. Small trials suggest some people have less digestive discomfort on A2 milk, but broader health claims are not proven.

Murrah buffalo

Quick take

  • A2 milk = only A2 beta-casein, no A1.
  • From buffalo, most desi cows, goats and others.
  • Holstein and Jersey carry A1.
  • Evidence: some digestive benefit; big claims unproven.

“A2” is now printed on milk, ghee and even curd. Here is what it actually refers to.

We make A2 buffalo bilona ghee; A2 ghee is explained in what is A2 ghee.

Beta-casein, A1 and A2

Milk protein is mostly casein, and about a third of that is beta-casein. It comes in variants; the two common ones, A1 and A2, differ at a single position in the protein chain. When A1 beta-casein is digested it can release beta-casomorphin-7 (BCM-7); A2 releases far less.

Which animals give A2 milk

AnimalBeta-casein
Buffalo (Murrah)A2 — all 172 tested A2A2 in a 2023 study (details)
Indian desi cowsMostly A2; some herds carry A1 (A2 cow breeds)
Holstein Friesian, JerseyA1 and A2 mix (Jersey milk)
Crossbred cowsVariable; A1 common

What the evidence says

EFSA’s 2009 review found no established cause-and-effect link between BCM-7 and chronic diseases. Smaller human trials, including a 2014 crossover study and a 2016 Chinese trial, reported less bloating and softer digestive symptoms for some people on A2-only milk. So A2 milk may help people who feel uncomfortable with regular milk; it is not a cure for anything (A2 milk benefits, the research).

A2 milk is not lactose-free

A2 concerns a protein. A2 milk has normal lactose, so it does not solve lactose intolerance (lactose).

From A2 milk to A2 ghee

Ghee is almost pure fat with only trace protein, so “A2 ghee” mainly tells you the milk source. That is still useful as a marker of breed and sourcing (A2 buffalo ghee, A2A2 testing).

A2 and ghee nutrition guides

Sources & references

  1. EFSA. Review of the potential health impact of β-casomorphins and related peptides. EFSA Scientific Report 231, 2009
  2. Ho S et al. Comparative effects of A1 versus A2 beta-casein on gastrointestinal measures. European Journal of Clinical Nutrition, 2014
  3. Jianqin S et al. Effects of milk containing only A2 beta casein versus milk containing both A1 and A2 beta casein proteins. Nutrition Journal, 2016
  4. Kathiravan P et al. A study on β-casein gene polymorphism in crossbred cattle and Murrah / graded Murrah buffalo in Tamil Nadu. Indian Journal of Animal Research, 2023; 57(7)
  5. Sodhi M et al. Screening of taurine and crossbred breeding bulls for A1/A2 variants of β-casein gene. Indian Journal of Animal Sciences, 2012; 82(2)

Frequently asked questions

What is A2 milk?

Milk whose beta-casein protein is only the A2 type, without A1.

Is buffalo milk A2 milk?

Yes. A 2023 study found all 172 Murrah buffaloes tested A2A2.

Is A2 milk healthier?

Some small trials show less digestive discomfort for some people; broader health claims are not established.

Is A2 milk lactose-free?

No. It contains normal lactose.

A2 by nature, in ghee form

A2 Farmer Buffalo Bilona Ghee — A2A2 confirmed by PCR, 99.76% milk fat, hand-churned and glass-packed. From ₹799.

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